Description
Product Characteristics: H2AFO, HIST2H2AA, H2A.2, H2A/q, HIST2H2AA4, H2A Histone Family Member O
Target Information: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling